How much do you really know about that multivitamin or herbal remedy you religiously take every day? Did you ask for your doctor’s approval prior to taking them?
 
A dietary supplement is a substance that is intended to provide nutrients not available in adequate amounts in a diet. The "dietary ingredients" in supplements may include: vitamins, minerals, herbs or other botanicals, amino acids, and substances such as enzymes, organ tissues, glandulars, and metabolites. (Dietary Supplement Health and Education Act (DSHEA) of 1994)
 
If you have an inadequate diet you may need to take supplements to fill in the blanks, provided your physician has approved them for you. For instance -
 
Inadequate diet e.g., Vegetarians often have iron deficiency due to lower availability of iron from vegetarian foods they consume.
Illness & subsequent inability to take food orally, e.g., in the case of post operative surgery, or cancer therapy.
Pregnancy e.g., prenatal vitamin and mineral supplements may be required during pregnancy to help in the growth of the foetus. Women planning to conceive should take adequate folate prior to becoming pregnant to ensure the good health of the foetus.
Children may need certain vitamins/ minerals to prevent nutrient deficiencies that may result in poor growth/ physical disability. These are administered by paediatricians at different stages of growth, when and only if deemed necessary.
Menstruation: Heavy menstrual bleeding can cause anemia in women. During the premenopausal stage in women there is a greater need for iron.
Mal-digestion and absorption of nutrients from whole foods e.g. in celiac sprue patients who may need water soluble forms of vitamin A,D,E and K as their bodies may not be able to absorb these vitamins in their natural form.
 
 
Rule # 1. Go with your gut feeling. For instance, if something sounds too good to be true, it probably is. The following examples of current supplement product labels are precisely that... Too good to be true!
Do some of these claims sound familiar...
 
“Totally safe," "all natural," and "definitely no side effects."
“Quick and effective”, "cure-all."
Can treat or cure disease.
Limited availability, "no-risk, money-back guarantees,"
“Fat Grabber” and “Fat Buster” pills that are 100% natural.
“Too skinny! take these pills guaranteed to work, or just grab those “Muscle Enhancer” orange pills, that help you gain weight and bulk up your muscles.
“100% of your days nutrient needs + herbal appetite suppressant.”
 
Supplements can never provide ALL the nutrients that one gets from fresh fruits, vegetables, whole grains, proteins and dairy.
 
Regulations for supplements are now becoming stricter in the US, and globally there are a few laws in the pipeline, but money spent on enforcement is no match when compared to the marketing blitz that sells these products.
 
Some common supplements and their examples are... (These will be discussed at length in Part 2 & Part 3)
 
Vitamins Minerals Herbs & botanicals Ayurvedic supplements Traditional Chinese Medicine (TCM)
http://
dietarysupplements
.nlm.nih.gov/dietary/
vitaminIngred.jsp
http://
dietarysupplements
.nlm.nih.gov/dietary/
mineralIngred.jsp
http://
dietarysupplements
.nlm.nih.gov/dietary/
betaHerb.jsp?list=all
   
Beta-Carotene Calcium (Shelcal, Macalvit) Glucosamine and/or Chondroitin Sulfate Gymnema sylvestre Ginkgo biloba
Multiple Vitamin/ Mineral A-Z (Revital) Iodine Acidophilus Black Cohosh Ashwagandha (Withania somnifera) Astragulus root (huang qi)
Folic Acid (folate) Iron (Fefol) Ginger Aamalaki (Emblic myrobalan) Panax ginseng
Vitamin A Magnesium Saw Palmetto Amla Gecko
Vitamin B Complex (Becosule) Potassium Evening Primrose Oil Brahmi (hydrocotyle asiatica) Ma huang (active ingredient aka Ephedra)
Vitamin C Selenium Echinacea Chandanam (sandalwood, Santalum album) Dong quai
Vitamin D Sodium Fiber Haldi (Turmeric, Curcuma longa/ domestica)  
Vitamin E Zinc St. John's Wort Guggulu  
Vitamin K   Garlic Triphala  
Omega-3 Fatty Acids (Cadvion)   Fish Oil Boswellia  
      Neem  
 
Q. Who is responsible for ensuring the safety and efficacy of dietary supplements?
Answer: The Manufacturer of the product and not a Federal regulatory body.

A lot of supplements specially “Herbal” are used extensively in Complementary and Alternative Medicine (CAM) practices such as Ayurveda, Naturopathy and Traditional Chinese medicine.

Because there is little regulation of these supplements, Health shops abound in them. In the USA, the Food and Drug Administration (FDA) has a say in the claims made by dietary supplement manufacturers only after they enter the market. The onus of making sure that a supplement is safe and that the claims made by the manufacturer are true lies with the manufacturer. This is because supplements are not considered to be a drug, even though they act like a drug.

Organizations such as the Health Foods and Dietary Supplement Association of India (HADSA) which was established in 2002 are trying to promote awareness and laws to bring some kind of order in this area. The Indian Food Safety and Standards Bill was also signed into law in 2005 to deal with this issue, but enforcement is inadequate.

Below are a few examples of how some supplement ingredients, including nutrients and plant components, can be toxic and have severe reactions:
 
Calcium and heart medicine (e.g., Digoxin used to treat irregular heart beat) individuals taking Digoxin should be careful with calcium supplement intake as high levels of calcium can cause a toxic reaction, while low calcium levels make the drug ineffective.
Taking Calcium supplements while on the antibiotic gentamycin can potentially increase risk of damage to the kidneys from the antibiotic
Magnesium and thiazide and loop diuretics (e.g., Lasix®, etc.), some cancer drugs (e.g., Cisplatin, etc.), and magnesium-containing antacids.
Coumadin a blood thinner & supplements - Vitamin K supplements interfere and can impede effectiveness of blood thinners. On the other hand Ginkgo biloba (an herbal supplement), aspirin (an OTC drug) and vitamin E (a vitamin supplement) can each thin the blood, and taking any of these products together with Coumadin can increase the potential for internal bleeding.
St. John's Wort and cyclosporine: St John’s Wort should not be taken with cyclosporine, an immunosuppressant drug taken by transplant patients, as it can reduce effectiveness of the drug and cause rejection of the transplanted organ.
St John’s Wort and Antidepressants: People on antidepressants must consult their physician prior to taking St John’s Wort as it amplifies the antidepressant activity of the medication.
The herbal remedy Arnica has a toxic effect on the heart and causes very high blood pressure.
 
8 Safety tips for Supplements -
 
1. Do not self-diagnose any health condition or substitute a dietary supplement for a prescription medicine or therapy, or for the variety of foods important to a healthful diet.
2. Just because they say 100% Natural on the bottle, Are they? The words ”Natural” “herbal” are used very loosely in the land of supplements!
3. Don’t fall for the latest celebrity endorsed advertisement for a supplement. Remember they are paid handsomely to endorse the product.
4. Supplements when taken in large doses or when taken incorrectly, can cause reactions similar to drugs.
5. Always consult your primary doctor before using any supplement, especially if you are taking any medications (whether prescription or over-the-counter).
6. Supplements are intended to fill in the gaps in a diet - not be an excuse for one. You cannot live off the myth of a miraculous supplement, period! And remember - more is NOT better! Large doses can occasionally be lethal.
7. Herbal supplements/remedies are still not understood very well, even though they have been around for a long time. Many people consider these substances to be natural herbs and therefore harmless. However, they are untested, unregulated and the effects from consuming them can be unpredictable, and in certain circumstances potentially toxic.
8. Bottom line! Given the potential pitfalls and in many cases lack of factual scientific data, shouldn't we pause and seek the advice of our physician prior to starting a supplement regimen.
 
Upcoming Issues:
Part 2: Categories and properties of Nutritional supplements.
Part 3: Herbal remedies: Claims, Myths, Facts
Part 4: Supplements: The good, the bad and the ugly. How to be an educated consumer.
 
Note: The examples provided do not represent an endorsement or approval by NutritionVista. The information provided is based on careful consideration by a team of dieticians to benefit and make the consumer aware of available products and their side effects. We recommend that if you are currently on any supplement not prescribed by your physician, or want to start taking one, please do consult with your primary care physician before doing so.

By Ms. Meenakshi Hejmadi MS, RD, Dietitian, NutritionVista.com
 
 
Bangalore, Lucknow, New Delhi, New York
www.NutritionVista.com